Milk Thistle Extract Silymarin Functional Ingredient for Health & Wellness

• Customization: Available
• Certification: ISO, HACCP, Halal
• Assay Method: HPLC
• Application Form: Lotion, Tablet, Capsule
• Application: Food, Health Care Products, Medicine, Cosmetic Ingredients
• State: Powder
• Extract Source: Milk Thistle
• Part of The Plant Used: Seed
• Mesh Size: 95% Through 80 Mesh
• Appearance: Light Yellow to Light Brown Powder
• Latin Name: Silybum Marianum (L.) Gaerth
• Transport Package: Pack in Paper-Drums and Two Plastic-Bags
• Specification: 25 Kg/drum
• Trademark: Sunfull
• Origin: P. R. China
• Production Capacity: 100 Tons Per Year

Product Description

Product Description

Milk Thistle Extract

Latin Name                     Silybum marianum (L.) Gaerth

Family                          Compositae

Part of the Plant Used             Seed

    

Product Introduction

Milk thistle originally is from Europe, the ingredient responsible for milk thistle's medicinal qualities is called silymarin. Silymarin is a flavonolignans that has been introduced fairly recently as a hepatoprotective agent, it is the most well known compound of the flavonoids, thanks to its well defined therapeutic properties, and in reality it is a mixture of three structural components: silybin or silybinin, Isosilybin, silydianin and silychristin, studies in animals have shown that silymarin promotes the following activities:

Liver Cell Growth ------ Silymarin from milk thistle appears to promote the growth of some types of cells in the liver. Milk thistle is not used to prevent Hepatitis C Virus from causing liver disease. Rather, milk thistle is used with the hope that it would minimize the damage to the liver that HCV can cause.

 

Antihepatotoxic Activity ------ Studies suggest that silymarin from milk thistle can block various types of toxins from entering and injuring liver cells.

 

Antioxidation ------ Milk thistle Silymarin may be an effective "antioxidant," which means milk thistle may help fight a destructive chemical process in the body known as "oxidation." In oxidation, harmful substances produced in the body (called free radicals) can damage cells. Some studies suggest that milk thistle silymarin can prevent these substances from damaging liver cells.

 

Inflammation Inhibition ------ Milk thistle's Silymarin is thought to prevent inflammation (swelling) of the liver; this may be described as displaying anti-inflammatory properties.

Silybin is the major active constituent of silymarin, both in vitro and animal research suggest that silibinin has hepatoprotective (antihepatotoxic) properties that protect liver cells against toxins, has also demonstrated anti-cancer effects against human prostate adenocarcinoma cells, estrogen-dependent and -independent human breast carcinoma cells,etc.

 

Common Milk thistle extracts is alcohol soluble, but poor soluble in water. Bioavailability of silymarin led to the development of enhanced formulations all over the world. Besides the common grade, We, Sunfull company also can supply the Water-Soluble Milk Thistle Extract, which adopts special manufacture process, so it has good solubility in water and can safely be added either into capsule, tablet or into beverage, and it has been marketed widely in P.R. China, Korea and Europe for years.

Active Ingredients

Product Specification

Basic Information

Silymarins(Silychristin,Silydianin,SilybinA&B,Isosilybinin A&B,Dehydrosilybinin)/ Silybins

 

80% Silymarins(UV)/30% Silybins (HPLC)

70% Silymarins(UV)

Water-Soluble Milk Thistle Extract 40%

 

Molecular formula: C25H21O10      

Molecular weight: 481.43

CAS No.: 22888-70-6

HPLC Chromatogram of Milk Thistle Extract 50% Silymarins / 30% Silybins

Physiological Functions

- Liver Diseases, acute, chronic hepatitis 
- Protect liver from toxins, heavy metals, alcohol, poisons 

- Anti cancer
- Cholagogue 
- Fatty degeneration of the liver 
- Jaundice 
- Psoriasis 
- Uterine tonic, menstrual difficulties 
- Spleen, kidney, gall bladder tonic 
- Varicose veins

Toxicity&Applications

Toxicity

The acute toxicity of silymarin and silybin were investigated by oral and intravenous route in various animal species. No mortality or any signs of adverse effects were observed after silymarin at oral doses of 20 g/kg in mice and 1 g/kg in dogs. The 50% lethal dose (LD50) after intravenous infusion values are 400 mg/kg in mice, 385 mg/kg in rats and 140 mg/kg in rabbits and dogs. These data demonstrate that the acute toxicity of silymarin is very low. Similarly, its subacute and chronic toxicity are very low; the compound is also devoid of embryotoxic potential.

 

Applications

l Functional food and food additive

l Herbal beverage ingredients

l Pharmaceutical stuff

Packing & Delivery

Pack in Paper-Drums and Two Plastic-Bags

Company Profile

Hunan Sunfull Bio-tech Co., Ltd

Founded in 2008, Hunan Sunfull Biotech specializes in the deep development of active ingredients from tea and natural plants. Backed by national research centers and partnerships with top universities like Hunan University of Chinese Medicine, we focus on innovation and the natural health industry.

Sunfull owns two independent production facilities certified with ISO9001, ISO22000-HACCP, Halal, Kosher, BV, and Sedex. With a food production license covering botanical instant beverages, tea products, and food additives, our products are widely sold both in China and overseas.

Our GMP-standard workshop is equipped with advanced technologies such as membrane separation, spray/freeze drying, and granulation, supporting applications across nutrition, cosmetics, and pharmaceuticals.

Beyond supplying plant extracts and traditional herbal compounds, we also offer technical support, formulation, and regulatory consulting.

We look forward to cooperating with partners in food, beverage, health, and cosmetics industries to deliver innovative, nature-based solutions for better human health.