Huperzia Serrata Extract Factory Supply 1.0% Huperzine a CAS 120786-18-7

• Certification: ISO, HACCP, Halal , Kosher, SGS
• Assay Method: HPLC, UV
• Application Form: Tablet, Capsule
• Application: Food, Health Care Products, Medicine
• State: Powder
• Extract Source: Huperzia Serrata
• Model NO.: SF-HSE001
• Transport Package: 25kg/Paper Drum
• Specification: 1.0% Huperzine A
• Trademark: Sunfull
• Origin: China
• HS Code: 2938909090

Product Description

                       Huperzine A
 

Latin Name                       Huperzia serrata
Chinese Name                     She Zhu Shishan
Family                                     Huperziaceae
Part of the Plant Used            Whole Herb
CAS No.:                       120786-18-7
Molecular formula:              C₁₅H₁₈N₂O
Molecular weight:                242.32
   
Product Introduction
Huperzine A, is a naturally occurring sesquiterpene alkaloid compound found in the plant firmoss Huperzia serrata. Huperzine A is an Acetylcholinesterase inhibitor similar to other compounds donepezil, rivastigmine, and galantamine. In the US, Huperzine A is sold as a dietary supplement for memory support. The botanical has been used in China for centuries for the treatment of swelling, fever and blood disorders. Clinical trials in China has shown it to be effective in the treatment of Alzheimer's disease, and has been shown to enhance memory in healthy young students in one study. "Huperzine A is a promising drug for symptomatic treatment of Alzheimer's disease."

Active Ingredients                Huperzine A
Product Specification             1.0% Huperzine A

Molecular Structure of Active Ingredients     


HPLC Chromatogram of 1.0% Huperzine A
 

   
Physiological applications

Traditional/Ethnobotanical uses
The club moss H. serrata has been used in Chinese folk medicine under the name Qian Ceng Ta (Chien Tseng Ta), for the treatment of bruises, strains, swelling, and fevers. It also has been used for schizophrenia.

Alzheimer disease
Huperzine A is being studied for potential use in treating Alzheimer disease. Human clinical studies of huperzine A for Alzheimer disease have been conducted only in China. Clinical studies of patients with mild to moderate Alzheimer disease found that huperzine A improved cognitive function, activity of daily life, and noncognitive disorders. In one study of mild to moderate Alzheimer disease patients, huperzine A was found to improve cognitive function, activity of daily life, and noncognitive disorders in a 12-week period compared with placebo. Because of possible activities in the brain, huperzine A also is being considered for potential use in preventing nerve gas poisoning. There are no clinical studies to date to verify its effectiveness in nerve gas poisoning. More clinical studies are needed to document the health benefits of huperzine A.

Applications

1. Pharmaceutical stuff
2. Functional Food and food additive

Availability
Huperzine A is sold either by itself in dosages of 0.05 mg, or in lower dosages combined with other mind-boosting nutrients.

Recommendations
Huperzine A appears to be a promising alternative to cholinesterase inhibitor drugs used in Alzheimer's disease. More studies are required to determine its long-term safety and side effect profile. Until we learn more about this herbal extract, I would recommend its use be limited to the therapy of AD, and preferably under medical supervision.