Eucommia Ulmoides Extract (Chicken feed grade)

• Certification: ISO, HACCP, Halal , Kosher
• Assay Method: HPLC, UV
• Application Form: Paste, Tablet, Capsule
• Application: Chicken Feed
• State: Powder
• Extract Source: Eucommia Ulmoides Extract
• Model NO.: SF-EUE001
• Mesh Size: 80 Mesh
• Transport Package: 25kg/Paper Drum
• Specification: SF
• Trademark: Sunfull
• Origin: China
• HS Code: 2938909090
• Production Capacity: 2000 Ton/Year

Product Description

Eucommia Ulmoides Extract (Chicken feed grade)


Latin Name                     Eucommia ulmoides Oliver
Chinese Name                     Du Zhong
Family                         Eucommiaceae
Part of the Plant Used            Leaves
Active Ingredients & Contents
3% ~ 6% Chlorogenic acid  
20% ~ 30% Flavonoids
30% ~ 45% Polysaccharides

1  Eucommia Ulmoides Extract Additives' Antimicrobial and Growth-promoting Effects on Broiler Chicken
Divide 825 Avian Broilers into five groups, five repeat in each group, feed with Eucommia Ulmoides Extract and Avilamycin (a state-permitted antibiotic) additives in daily ration, for feeding experiment from newborn to 42 days age, the experiment is divided into two stages. The experiment shows Eucommia Ulmoides Extract additive ratio of 0.15%, 0.2% and 0.25% in daily ration has no significant influence on growth performance of 0~6 weeks age Avian Broilers. But their influence on meat quality is evident. The slaughter rate of Eucommia Ulmoides Extract experimental group is higher than those of Avilamycin group and blank control group. The half-eviscerated and eviscerated rates of experiment group with 1500mg/kg Eucommia Ulmoides Extract additives in daily ration are 3.25% and 5.00% respectively higher than those of control group, but when analyzing the indicators after slaughter, the difference between groups has not reached to a significant level (p>0.05). Blood indicators show that low dose of Eucommia Ulmoides Extract additive can reduce the urea protein content in blood, and is beneficial for absorption and utilization of nitrogenous compounds. This experiment also shows that it's not suitable to add high dose Eucommia Ulmoides Extract in daily ration of broilers.

2  Eucommia extract's mould proof effect study
Add 0.15% pure Eucommia powder (as active ingredient 8g) to feed, it can effectively prevent the feed mildewing. The mold multiply in feed, which kept for 45~60days in the condition: between July and September, at room temperature 27-38°(average 31.5°), relative humidity 50-84%.Without preservatives feed, the total mold is 5.0 × 10⁵cfu/g. added pure Eucommia powder feed, the total mold is 1.7 x 10⁵cfu/g. But the feed with Luprosil Salt (main calcium propionate) and Confeed (composite mold inhibitor), the total mold is 2.3×10⁵cfu/g and 2.8 × 10⁵cfu/g. The result indicate that feed with pure Eucommia powder, its total mold is significantly lower than the other three groups (P <0.01), the inhibition rate of mold by pure Eucommia powder is 78.2%.

3  Safety evaluation test report
Toxicological safety determination of pure Eucommia powder
1. General toxicological test
Acute toxicity test
Do acute toxicity test on Kunming mice, which are provided by Hunan Institute of Pharmaceutical Industry. With high concentration solution of pure Eucommia powder to irrigation stomach, determinate its LD50. The result turn out that there is no death and could not determinate LD50. The oral maximum tolerated dose (MTD) is greater than 27788.0mg/kg, weight (1.54-1.74 times mouse body weight) LD50 of intraperitoneal injection is 2610.0mg/kg. It indicates that the pure Eucommia powder is very low toxicity.

The chronic toxicity tests of Eucommia bark extract (pure powder)
According to the maximum tolerance dose of acute toxicity test, use 6.17, 2.06, 0.69g/kg Eucommia bark extract on mouse respectively, take for 8-week, results showed that it has no effects on mouse and its Blood conventional index; and there is no significant difference on normal blood with the control group (P > 0.05), but Eucommia bark extract has certain inhibition of growth on mouse if it takes high dose, the content of total protein, albumin, urea nitrogen in the blood was significantly higher than other groups, however, low doses of eucommia bark extract on the growth of the middle mouse has a significant role in promoting, the activity  of GOT, GPT and ALP in the blood will decline with the increase of the dose, and there has very significant difference with blank control group(P < 0.01). So, eucommia bark extract  can reduce the blood of the active, improves the digestive system function.  Low doses of eucommia bark extract can reduce the content of urea nitrogen in the blood, improve the efficiency of nitrogen absorb, and no adverse effects to other organs.


2. Special toxicity tests
The reproductive toxicity tests of eucommia ulmoides extract
The Ames tests of eucommia ulmoides extract
The bone marrow micronucleus test of of eucommia ulmoides extract
The Sperm deformity test of eucommia ulmoides extract
Through tested mouse mating, pregnancy, birth, young survive, young mouse growth observation, examined disease of  the mouse uterus, ovaries,  fallopian tube and other organs and tissues, biopsy and the quantity of sperm deformity, no matter the high dose or low doses of eucommia bark extract on the reproductive organs and reproductive functions of the mouse, all without adverse effects, also won't mutate carcinogenic and teratogenic.

Microbial
Total Plate Count	NMT 1,000cfu/g	Conforms	GB/T 4789.2 -2020
Total Yeast & Mold	NMT 100cfu/g	Conforms	GB/T 4789.15-2020
E. Coli	Negative	Conforms	GB/T 4789.3 -2020
Salmonella	Negative	Conforms	GB/T 4789.4 -2020
Packing & Storage	Pack in paper drum and two plastic bags inside. Net Weight: 25 kg/drum. Store in a well-closed container away from moisture.